Although/though
Although/though can be used to contrast ideas. Although/though are subordinating conjunctions used to connect a subordinate clause to a main clause, like after, as, before, if, since, that, even though, even if.
Even though, even if
Even though and even if are also used as subordinating conjunctions in the same way as although/though. Even though is similar to although but it makes a stronger contrast:
Despite / in spite of
We use 'despite' or 'in spite of' before a noun or a gerund. It can also go in the middle or at the beginning of a sentence. 'Despite' and 'in spite of' mean exactly the same thing. You can choose whichever one you like! If you want to use 'despite' or 'in spite of' before a clause, you need to add 'the fact that'.
However
We use 'although' and 'despite / in spite of' to connect two clauses in the same sentence. On the other hand, 'however' isn't used to connect two clauses. Instead, we usually put the two ideas in two separate sentences. We put 'however' in the second sentence, and we can put it at the beginning, at the end, or after the subject.
Nevertheless
We can use either of the adverbs however or nevertheless to indicate that the second point we wish to make contrasts with the first point. The difference is one of formality: nevertheless is bit more formal and emphatic than however.

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